Sir Robert Salusbury d. in 1599, and on the death in 1608 of his son, JOHN SALUSBURY, without children, captain John Salusbury, the young man's uncle, inherited the estates. He, however, d. without issue three years later, in 1611, to be succeeded by another brother, WILLIAM SALUSBURY (known in later years as ‘Hen Hosanau Gleision,’ i.e. ‘Old Blue Stockings’). Sir Robert and the captain had spent extravagantly during their thirty-year tenure of the estates, and William found them heavily mortgaged. In another thirty years of hard work and frugal living he paid off his debts, restored his inheritance, and even added to it. Then, because of a violent quarrel with his eldest son, OWEN SALUSBURY, over the latter's marriage to Mary, daughter of Gabriel Goodman of Abenbury, prothonotary of North Wales, William split his estates into two parts, giving Rug and the Merionethshire lands to Owen, and Bachymbyd and the Denbighshire lands to his second surviving son Charles. William was one of the king's staunchest supporters in the Civil War; he repaired Denbigh castle at his own expense in 1643, and, although advanced in years, defended it stubbornly against the Parliamentary army. It was not until 26 Oct. 1646, after a siege lasting six months, that he was forced to surrender the castle to general Mytton — and would do so then only after he had received the king's written command. William, whose wife was Dorothy, daughter of Owen Vaughan of Llwydiarth, had been Member of Parliament for Merionethshire in 1620-22; he d. in 1660. Owen Salusbury, the eldest son, followed a vacillating course during the Civil War; he was sheriff of Merioneth in 1647-8. He d. 17 Jan. 1657/8, transmitting the Rug estates to his eldest son WILLIAM SALUSBURY, who served as sheriff of Merioneth in 1661-2, and d. in 1677. He was succeeded in turn by his son OWEN SALUSBURY, who, after having become a Roman Catholic, d. in 1694, leaving two daughters. ELIZABETH, the elder, who inherited Rug, m. Rowland Pugh of Mathafarn in Cyfeiliog. They had one son, WILLIAM PUGH SALUSBURY, who d. unmarried, and two daughters. The estate was inherited by the elder of the two, MARIA CHARLOTTE (1721-1780), who m. firstly Thomas Pryce of Gogerddan (d. 1745), and secondly, the Rev. John Lloyd. When she d. on 26 Aug. 1780 she left Rug by will to Edward William Vaughan, second son of Sir Robert Howel Vaughan of Nannau and Hengwrt (see the article on that family); he d. in Sicily in 1807, and the estate passed to his younger brother, Griffith Howel Vaughan. When Griffith d. in 1848 it was inherited by his nephew, Sir Robert Williames Vaughan of Nannau and Ystumcolwyn, from whom it passed to Charles Henry Wynn (1847-1911) of Glynllifon, third son of Spencer Bulkeley Wynn, 3rd baron Newborough (see Glyn of Glynllifon family, and Wynn of Rug family).

CHARLES SALUSBURY, second surviving son of the defender of Denbigh castle, was a staunch royalist like his father, and was nominated a Knight of the Royal Oak in 1660. His only surviving child, JANE SALUSBURY, heiress to Bachymbyd, carried that estate in marriage in 1670 to Walter Bagot, eldest son and heir and successor to Sir Edward Bagot, 2nd bt., of Blithfield, Staffordshire. Jane's cousin, William Salusbury of Rug, foreseeing that this marriage would end all hope of reuniting the Rug and Bachymbyd estates in a member of the Salusbury family, waged a long and bitter but unsuccessful legal battle with Jane's husband for possession of Bachymbyd, in the course of which Gabriel Salusbury, William's brother, had to flee abroad in consequence of having procured the forgery of a deed.